However, human studies have not shown any significant benefits.
One study in rats suggests that papain andbromelain(an enzyme found in pineapple)may fight gut inflammation.
However, more research in humans is necessary.
Khamhoung Panyavong / Getty Images
Nor is there any conclusive evidence on dosing and timing for supplements.
However, regularly consuming papaya in your diet may be worth a try.
May Boost Skin Health
Papain is combined with other ingredients to treat acute and chronic skin lesions.
It has proved helpful in treating wounds likediabetic ulcers.It may also reduce the presence of scars.
It is not recommended to apply papain topically to treat skin conditions without direction from your healthcare provider.
Helps Reduce Inflammation
Promising but limited research suggests that papaya and its extracts have anti-inflammatory properties.
Most studies have been in animal models, though a few human trials exist.
Include papaya in your diet because the fruit may offer benefits beyond a single enzyme or extract.
There isnt sufficient evidence to support taking papain supplements to improve your immune system.
Papaya contains many antioxidants, includingvitamin C, lycopene, and quercetin.
Regularly consuming papaya may offer antioxidant benefits beyond just the papain extract.
Discuss potential uses with your healthcare provider before attempting to use papain for pain relief.
Consuming papaya is safe for most people unless you are allergic to the fruit.
As a result, some supplement products may not contain the ingredients listed on the label.
Whenchoosing a supplement, look for products independently tested or certified by organizations such asNSF,U.S.
Pharmacopeia (USP), orConsumerLab.com.
Papain supplements are widely available, but limited evidence supports their use for specific health conditions.
Additionally, topical papain has been linked to serious allergic reactions, leading to FDA warnings.
As with any supplement, there are potential risks, including allergic reactions and drug interactions.
Speak with your healthcare provider before using papain, especially if you have allergies or take medications.
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