Urine therapy, or urotherapy, refers to the use of urine in alternative medicine.
Urine containsurea, a substance produced in the liver.
This article answers the question of whether urine can clear acne.

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Despite its traditional uses, you would be hard-pressed to find scientific evidence in support of urine therapy.
In short, that’s because there is none.
As for urine being acidic and drying up pimples, that’s not accurate either.
Urine is a very weak acid.
Nothing about it could dry up a pimple.
What Pee Is Made Of
About 95% of urine is water.
Urea gets a lot of attention in the world of dermatology.
It is:
There is a major catch, however.
So, an actual skin care product is still the best way to get it.
What Is a Urine Rub?
A urine rub is a method of using urine to exfoliate the face.
Note that there is no evidence that urine rubs are safe or effective for healing any skin issues.
Putting pee on your face is neither safe nor hygienic, and may make your acne worse.
Contrary to popular belief, your urine is not sterile.
There are low levels of bacteria even in a healthy person’s pee.
This doesn’t mean it’s toxic.
And if you have questions or need help, ask your healthcare provider.
Summary
Urine contains about 95% water, 2% urea, and trace amounts of minerals.
Synthetic urea is used in skincare products due to its proven moisturizing, exfoliating, and antimicrobial properties.
Human urine does not contain high enough concentrations of urea to be effective.
2015;8(10):47-8.
2015;68(2):173-4.doi:10.1016/j.eururo.2015.02.041