Anything higher than 25 milligrams should be discussed with a healthcare provider.
As a general rule, speak with your healthcare provider before taking alcohol in any form with MTX.
Patients taking Tylenol (acetaminophen) regularly should be cautious about their alcohol use.

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Therefore, its safest not to exceed 3,000 mg per day, especially for people with lower body weight.
Overuse of alcohol with NSAIDs can also increase the risk of stomach ulcers.
Exceeding the recommended dosage of medications like ibuprofen and aspirin can irritate your stomach lining.
Drinking alcohol in combination with NSAIDs increases this risk and may lead to internal stomach bleeding.
Drinking alcohol in the evening may adversely affect the quality of sleep.
Poor sleep can increase the symptoms offibromyalgiasuch as fatigue, pain, headaches, and depression.
Dr. Zashin is also an attending physician at Presbyterian Hospitals of Dallas and Plano.
Dr. Zashin is the author ofArthritis Without Pain: The Miracle of Anti-TNF Blockersand co-author ofNatural Arthritis Treatment.
American College of Rheumatology.Methotrexate (Rheumatrex, Trexall, Otrexup, Rasuvo).