Combining these drugs can increase the risk of side effects such as drowsiness, dizziness, and impaired coordination.
A healthcare professional can recommend alternative approaches or different medications.
This article will discuss using Zyrtec and Benadryl and the precautions for combining medications to help manage your allergies.
Getty Images / FatCamera
Getty Images / FatCamera
How Are Zyrtec and Benadryl Used?
Both medications are generally safe and effective when taken alone.
Benadryl was created in the 1940s and is considered a first-generation antihistamine.
In 1995, Zyrtec came to the market.
As a newer medication for allergies, it was considered a second-generation anti-allergy medication with less sedating effects.
Second-generation allergy medications are generally preferred over first-generation ones due to the lower risk of sedating effects.
Can I Take Zyrtec and Benadryl Together?
You should not combine multiple antihistamine medications, such as Zyrtec and Benadryl.
However, in some cases, you may need additional relief.
Talk to your primary care provider before starting another medication to see what is best for you.
After taking Zyrtec, you should wait at least 24 hours before taking Benadryl or another antihistamine.
However, Benadryl only lasts in the body for four to six hours.
How Much Zyrtec or Benadryl Should I Take?
This is enough to last 12 to 24 hours, depending on the persons allergies.
One pill is enough for daily relief, as it is effective longer than Benadryl.
Can I Combine Other Allergy Medications?
Generally, you should avoid taking two medications from the same class simultaneously.
Still, this may not provide any extra relief.
These are safe to take if you have already taken an antihistamine.
It is always best to speak with your primary healthcare provider before starting another medication for the same use.
What Other OTC Drugs Are Available for Allergy Symptoms?
Some examples of other antihistamines include:
Decongestantsare another throw in of drug class commonly used for allergy symptoms.
These can help relieve congestion.
Examples include:
Steroids are also effective drugs for allergies.
Frequently Asked Questions
Animal studies have not shown any harm from taking Zyrtec or Benadryl during pregnancy.
However, no human studies have determined these medications to be safe to take while pregnant.
If you are pregnant, ask your healthcare provider what options are most appropriate.
Other symptoms reported during overdoses have includedrhabdomyolysis, seizures, and heart-related problems.
The author would like to recognize and thank Jaycob Mathew Pena for contributing to this article.
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