Cardiovascular autonomic neuropathy(CAN) is a throw in of dysfunction commonly found in people withdiabetes.

It results from damage to the nerves that lead to theheartand blood vessels.

People with CAN may have increased risk of heart complications, includingarrhythmiasandheart failure.

Man consulting doctor about heart problems

kupicoo / E+ / Getty Images

This article discusses CAN symptoms, causes, diagnosis, and treatment options.

Symptoms such as light-headedness and vision disturbance upon standing are known asorthostaticintolerance.

When we stand, blood pools in the legs, causing a temporary decrease in blood pressure.

Orthostatic intolerance happens where there is a problem with this process.

What Is the Autonomic Nervous System?

Theautonomic nervous systemcontrols basic body functions that we rely on without even being aware of them.

This includes heartbeat, blood pressure, breathing, and digestion.

Causes

CAN is defined as an autonomic disorder in people with diabetes.

Poor blood sugar control over time damages nerves throughout the body, leading to neuropathy.

This is known asperipheral neuropathy.

Results from several types of tests are combined to arrive at a CAN diagnosis.

Complications

CAN has been associated with heart disease.

Treatment instead focuses on preventing further damage and managing symptoms.

Some medications, such asfludrocortisone,midodrine, ordroxidopa, may be used to help alleviate symptoms.

Having the understanding and support of your treatment team, family, and friends is important.

It can be noticed when standing up or exercising.

CAN is most often a complication of long-standing, uncontrolled diabetes.

CAN also increases the risk of heart complications like heart attack and arrhythmias, so prompt treatment is essential.

Oftentimes, multiple tests and specialist referrals are required.

All of this can be overwhelming and frustrating.

Specialized centers for autonomic disorders and support groups can be invaluable for people living with CAN.

doi:10.1136/bmjdrc-2021-002480

Serhiyenko VA, Serhiyenko AA.Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment.World J Diabetes.

2018;9(1):1-24. doi:10.4239/wjd.v9.i1.1

MedlinePlus.Autonomic nervous system disorders.

2020;13(4):1036-1054. doi:10.1016/j.jcmg.2019.01.042

Centers for Disease Control and Prevention.Diabetes: Nerve damage.

2021;21(1):e63-e67.

Olshansky B, Muldowney J.Cardiovascular safety considerations in the treatment of neurogenic orthostatic hypotension.American Journal of Cardiology.

2020;125(10):1582-1593. doi:10.1016/j.amjcard.2020.01.037