The bone marrow may not make enoughplatelets, or the immune system may destroy platelets inappropriately.

Certain medications such as chemotherapy drugs may also cause thrombocytopenia.

If the bone marrow is malfunctioning properly, it may not make enough platelets and cause thrombocytopenia.

Thrombocytopenia Risk Factors

Verywell / Dennis Madamba

If a platelet count falls below 150,000 per microliter of blood, it is considered thrombocytopenia.

Platelet Breakdown

Some health conditions can cause the premature breakdown of platelets in the body.

This can happen as a result of an autoimmune disorder or an infection.

Certain medications can also have this effect.

Trapped Platelets

Normally, about one-third of the platelets in the body will rest in thespleen.

However, sometimes certain conditions cause the spleen to hold on to a greater number of platelets.

This can happen without a known cause, but may develop due to other pregnancy-related complications such aspreeclampsiaorHELLP syndrome.

Genetics

Certain genetic conditions can lead to the development of low platelets.

Don’t take blood thinners unless your healthcare provider prescribes them.

ensure all your healthcare providers know about the medications and supplements you’re taking.

Some of these conditions include things like leukemia, viral infections, autoimmune disorders, and infections.

People with liver disease and people on chemotherapy drugs may also develop thrombocytopenia.

Risk factors for thrombocytopenia include heavy alcohol use and chemical exposure.

National Heart, Lung, and Blood Institute.Thrombocytopenia.

MDS Foundation.What is MDS?

2016;11(1):55-60.