There is no known cause of liposarcoma.

These genetic mutations occur sporadically (at random) or are acquired over a person’s lifetime.

They are not passed down from a parent.

An illustration with common liposarcoma risk factors

Illustration by Jake Shi for Verywell Health

There are some inherited genetic conditions that are known to increase a person’s predisposition for developing cancer.

Summary

There is no definitive cause of liposarcoma.

Know that there is nothing you could have done to avoid this very rare cancer.

Your healthcare provider can help you create a plan and a screening protocol that is right for you.

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American Cancer Society.Risk factors for soft tissue sarcomas.

National Cancer Institute.Adult soft tissue sarcoma treatment (PDQ)health professional version.

2019;26(1):1-7. doi:10.26444/aaem/94299