They are taken for similar purposes but work differently, with distinct benefits and potential side effects.
Common brand names for ibuprofen include Motrin and Advil.
COX-1 protects the stomach lining and regulates blood platelets, while COX-2 is primarily associated with inflammation and pain.

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By blocking COX enzymes, ibuprofen reduces the levels of prostaglandins, leading to decreased inflammation and pain relief.
Benefits
Ibuprofen offers many benefits, making it a popular choice for managing pain and inflammation.
Celebrex effectively manages pain and inflammation, but there are some side effects and risks.
The safety and effectiveness of Celebrex have been established for children ages 2 and older.
You cantake ibuprofen with foodor milk to help protect your stomach lining and reduce gastrointestinal discomfort.
Staying hydrated and avoiding alcohol can further reduce the risk of stomach and kidney issues.
Taking Celebrex with food can also help minimize stomach irritation.
Report any unusual symptoms or side effects to your healthcare provider as soon as possible for both medications.
Who Should Avoid Celebrex vs. Ibuprofen?
Both are types of NSAIDs, but they work differently.
No definitive clinical evidence suggests that one is better than the other.
Prescribers' Digital Reference.Advil (ibuprofen).
Prescribers' Digital Reference.Celebrex.
American College of Rheumatology.NSAIDs (nonsteroidal anti-inflammatory drugs).
Patient education:Nonsteroidal antiinflammatory drugs (NSAIDs) (Beyond the Basics).