It also regulates the menstrual cycle and supports reproductive health.
In males, estrogen levels remain steady after puberty and may slowly increase with age as testosterone levels decline.
Blood estrogen levels are measured in picograms per milliliter (pg/mL).

Guido Mieth / Getty Images
What Causes High Estrogen Levels?
Testing can help determine whether your estrogen levels are too high.
Treatment varies depending on your diagnosis and may include medications, lifestyle modifications, or surgery.
Diet
Dietary changes may help reduce estrogen levels and restore healthy hormonal balance.
Long-term, elevated estrogen can affect reproductive, sexual, bone, brain, and heart health.
See a healthcare provider if you have symptoms of high estrogen.
Early diagnosis and treatment can help restore hormonal balance and improve your health and quality of life.
Endocrine Society.What does estrogen do?
Cooke PS, Nanjappa MK, Ko C, et al.Estrogens in male physiology.Physiol Rev.
2017;97(3):995-1043. doi:10.1152/physrev.00018.2016
Endocrine Society.Reproductive hormones.
Delgado BJ, Lopez-Ojeda W.Estrogen.
StatPearls Publishing; 2024.
Schulster M, Bernie AM, Ramasamy R.The role of estradiol in male reproductive function.Asian J Androl.
2016;18(3):435-440. doi:10.4103/1008-682X.173932
Mayo Clinic Laboratories.Estradiol, serum.
2020;10(3):2045894020952019. doi:10.1177/204589402095202
Male Infertility Guide.Elevated estradiol and male infertility.
Rizner TL, Romano A.Targeting the formation of estrogens for treatment of hormone dependent diseases-current status.Front Pharmacol.
2020;11(11):CD013138.
Rakotomahenina H, Rajaonarison J, Wong L, Brun JL.Myomectomy: technique and current indications.Minerva Ginecol.
2017;69(4):357-369. doi:10.23736/S0026-4784.17.04073-4
National Cancer Institute.Types of cancer treatment.
U.S. Department of Veterans Affairs.Estrogen dominance.
Brown AMC, Gervais NJ.Role of ovarian hormones in the modulation of sleep in females across the adult lifespan.Endocrinology.
2020;161(9):bqaa128.