Understanding their differences and similarities can help you determine which option is best for you.

Contrave is not intended for use as a short-term weight loss solution.

It is a long-term treatment designed for therapy continuation.

‘Contrave’ pills.

Getty Images |Roberto Machado Noa/ Contributor

It is dependent on the initial treatment response.

Contrave is not recommended for those with severe liver or kidney disease.

One study assessed the efficacy of Contrave in combination with lifestyle modifications.

Participants receiving Contrave experienced 5% to 6% weight loss, significantly more than those on placebo.

Wegovy helps reduce appetite and cravings, improve insulin sensitivity, and promote significant weight loss.

Wegovy is a once-weekly injectable medication that belongs to a class of drugs calledGLP-1 receptor agonists.

Those with a history of pancreatitis should take Wegovy with caution and consult with a healthcare provider.

Which Is Better for Weight Loss?

Determining which medication is better for weight loss depends on several factors.

It should also be taken with caution in those with seizure disorders because bupropion lowers the seizure threshold.

Summary

Contrave and Wegovy are taken for similar purposes.

Their main differences lie in their mechanisms of action and how they are taken.

Contrave is a pill taken twice daily, while Wegovy is an injection administered once a week.

Additionally, Wegovy has been approved for use in children, whereas Contrave is only for adults.

Side effects vary between the two drugs.

Contrave’s bupropion component can potentially affect mood, while Wegovy is more commonly associated with gastrointestinal issues.

The best option depends on personal preference, health history, and weight loss goals.

Discuss your options with your healthcare provider to determine the best approach.

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MedlinePlus.Naltrexone and bupropion.

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