GABA supplements are believed to help reduce anxiety, improve sleep, and support relaxation.
It is found in foods like tea and cruciferous vegetables but is often taken in higher amounts through supplements.
That means some supplement products may not contain what the label says.
Verywell / Getty Images
Verywell / Getty Images
What Is GABA?
Gamma-aminobutyric acid (GABA) is an amino acid and neurotransmitter that the body naturally produces.
Function of GABA
As a neurotransmitter, GABA sends messages throughout the central nervous system.
No supplement is intended to treat, cure, or prevent disease.
Like many supplements, people may use GABA for various reasons.
However, there are several clinical trials assessing GABA for the following potential uses.
Blood Pressure
There are numerous small studies about GABAs effects on lowering blood pressure.
However, the results are mixed.
Supplement Facts
What Are the Side Effects of GABA Supplements?
As with many medications and supplements, side effects are possible with GABA.
Severe Side Effects
Presently, there are no studies that specifically assess GABAs safety.
But several clinical trials suggest that GABA isnt linked to severe side effects, except forlow blood pressure.
You may feel faint with low blood pressure.
Severe allergic reaction is another serious side effect possible with any medication or supplement.
If youre having a severe allergic reaction to GABA, get medical help immediately.
Symptoms may include breathing difficulties, itchiness, and rash.
Call 911 if your symptoms feel life-threatening.
They can help prevent possible interactions and side effects.
They can also ensure that youre giving GABA a fair trial at appropriate doses.
What Happens if I Take Too Much GABA?
There is limited information about GABA toxicity and overdoses.
The upper recommended intake is typically 3 grams per daywith no more than 750 milligrams per dose.
However, current research doesnt support 5-HTP and L-tryptophan to help with sleep.
Food Sources of GABA
you could get natural sources of GABA through your diet.
Drastic dietary changes may interact with your medications or affect your medical conditions.
For this reason, talk with your healthcare provider first.
They will help you safely make these changes.
GABA Supplements
GABA is available in many dosage forms, including capsules and tablets.
Each product may work differently depending on the form, so following the directions is essential.
Other Ways to Increase GABA
Mind-body practices might help boost your brain’s GABA levels.
Summary
GABA is an amino acid and neurotransmitter that may help improve your mood and sleep.
Several studies show that increased GABA levels in the brain can help decrease anxiety, stress, and depression.
However, very little GABA may cross the blood-brain barrier when taken in oral supplement form.
More research is needed to assess GABAs effectiveness and safety.
Before taking GABA, talk with your pharmacist or healthcare provider to help you safely achieve your health goals.
Diabetes Metab Syndr Obes.
2015 Feb 3;8:79-87. doi: 10.2147/DMSO.S50642
Cold Spring Harbor Laboratory.GABA Neurotransmitter.
2021;13(8):2742. doi: 10.3390%2Fnu13082742.
ClinicalTrials.gov.Effect of GABA on ADHD and seizures in children with epilepsy.
2018;2018:8109621. doi: 10.1155%2F2018%2F8109621
MedlinePlus.A guide to herbal remedies.
Briguglio M, Dell-Osso B, Panzica G.Dietary neurotransmitters: A narrative review on current knowledge.Nutrients.
Published 2021 Jan 21. doi:10.3389/fpsyt.2020.620097
National Institutes of Health Office of Dietary Supplements.Dietary supplement label database.
2020;26(3):190-197. doi:10.1089/acm.2019.0234
