But do peptide lip treatments actually work?

Peptidesare short chains of amino acids that serve as the building blocks of proteins like collagen and elastin.

Unlike traditionalmoisturizers, peptides hydrating effect doesnt come from sealing in moisture.

person holding up peptide lip treatment

Courtesy of Allison Tsai / Photo Illustration by Amelia Manley for Verywell Health

How Do Peptide Lip Treatments Work?

A 2023 study evaluated a facial serum containing neuropeptides, proteins, amino acids, and marine extract.

Your lips might also appear fuller when using peptides.

Are Lip Peptides Safe?

Peptides are generally low-risk and safe for lips and skin.

But its also important to consider the other lip treatment ingredients.

Some products may contain preservatives, fragrances, or other additives that could cause irritation, said Kopelman.

Are There Better Alternatives to Peptides?

These help prevent moisture loss and relieve dry or chapped lips.

Graf said you could also combine peptides with other ingredients to get that hydration.

Pairing peptides withhyaluronic acidor ceramides can be even more effective for an extra hydration boost.

If your goal is plumper lips, look for products that combine peptides with nourishing oils or shea butter.

Deza G, Gimenez-Arnau AM.Allergic contact dermatitis in preservatives: current standing and future options.Curr Opin Allergy Clin Immunol.

2017;17(4):263-268. doi:10.1097/ACI.0000000000000373