Calcium D-glucarate supplements are made by combining calcium and glucaric acid.

However, they contain little calcium and should not taken as a calcium supplement.

Other names for it include D-glucaric acid salt, calcium glucarate, and calcium D-saccharate.

A woman sitting on a bed with pills and a glass of water in her hand

Getty Images / ljubaphoto

That means some supplement products may not contain what the label says.

No supplement’s intended purpose is to treat, cure, or prevent disease.

Calcium D-glucarate is sometimes marketed as helping to prevent or reduce cancer.

Animal studies have shown that calcium D-glucarate may slow tumor development.

However, only mice and rats have been the subjects of these studies.

Taking calcium D-glucarate supplements by mouth blocks an enzyme called beta-glucuronidase.

Though calcium D-glucarate does contain some calcium, it is not intended for use as a calcium supplement.

Human vs.

Animal Studies

Animal studies are often conducted in non-human species such as mice, rabbits, or rats.

Although these studies often help further medical research, animal studies may not accurately predict human reactions or outcomes.

Therefore, they are not a sufficient substitute for high-quality clinical trials.

When reading about animal research, it is important not to draw conclusions based on the results.

More research is necessary to confirm any results found in animals.

Additionally, there is not enough research to provide a recommended dosage for calcium d-glucarate supplements.

Does Calcium D-Glucarate Interact With Any Drugs?

Drugs broken down by the liver (or glucuronidated) may interact with calcium D-glucarate.

Can You Get Calcium D-Glucarate in Your Diet?

The body naturally produces calcium D-glucarate in small amounts.

A well-balanced, nutritious diet is key to improving and maintaining your overall health.

Summary

Calcium D-glucarate is the calcium salt of d-glucaric acid, which the body produces naturally.

It is also found in certain foods, including fruits and vegetables, and marketed as a dietary supplement.

Consuming the right nutrients in your diet can benefit your overall health.

Memorial Sloan Kettering Cancer Center.Calcium glucarate.

1995;15(3):805-810.

Singh J, Gupta KP.Calcium glucarate prevents tumor formation in mouse skin.Biomed Environ Sci.

2003;16(1):9-16.

National Library of Medicine.Calcium-d-glucarate.Altern Med Rev.

2002;7(4):336-339.

2004;125(5 Suppl):149S-50S.