When digesting food, the stomach uses gastric acid to break food down.
PPIs stop acid from being produced.
The body responds by recognizing there isn’t enough acid and seeks to make more by producing more gastrin.
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Too much gastrin has been found to promote the growth of gastrointestinal tumors.
A 2019 study found that even whenH.
PPIs like Prilosec and Prevacid (lansoprazole) are available over the counter without a prescription.
But long term use can be problematic, even at the lower doses.
Alternatives to PPIs
Although PPIs are commonly prescribed in the U.S., there are alternative options available.
These can include lifestyle modifications, alternative therapies, and other medications.
H2 blockers are medications that lower the production ofhydrochloric acidin the stomach.
They are absorbed quickly and the resulting acid suppression lasts for several hours after the medications have been taken.
H2 blockers can also work to counter the effect of acid on the esophagus that causes heartburn.
H2 blockers include:
Antacids may be appropriate in some cases.
These drugs work by neutralizing stomach acid.
They are the oldest treatment for heartburn on the market.
Most antacids are a mixture of aluminum and magnesium hydroxide.
Some may also contain sodium bicarbonate.
Others can irritate the esophagus.
Always speak with your healthcare provider before discontinuing or changing any medications.
This may play a role in the development of gastric cancer.
Prevention strategies like stopping smoking and changes in diet may help manage GERD to avoid the need for medication.
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