Recreational drugs are also associated with ED.
Antidepressants and Other Psychiatric Drugs
The sexual side effects ofantidepressantsand other psychiatric drugs are well known.
Other types of psychiatric drugs can cause erection problems, includinganxiolytics(anti-anxiety drugs) andantipsychotics.

Verywell / Daniel Fishel
These include hormonal drugs used to slow the progression ofprostate cancer.
These medications have anti-androgenic effects, meaning that they block the action of testosterone or lower testosterone.
One of the common side effects of opioid drugs is ED.
The blockage of communication can lead to a steep drop in testosterone and an increased risk of ED.
Parkinson’s is thought to be sparked by an imbalance of acetylcholine and dopamine.
By altering the action of theseneurotransmitters, the excitatory nerves in the penis may be impaired.
Chief among these areantihistamines.
These not only include antihistamines used specifically to treat allergies but also those classified asH2 blockersthat function asantacids.
The overuse of antihistamines may lead to erection problems, particularly in those with other risk factors for ED.
Some impair signals to and from the brain that facilitate erections.
These include prescription medications and certain supplements that can reduce testosterone levels when overused.
Changing may be less reasonable if you are managing cancer or a serious heart condition.
Other factors may be at play.
OTC medications linked to ED include antihistamines, H2 blockers, and Sudafed.
If you believe that medications are causing your ED, speak with a healthcare provider.
Do not stop taking any prescribed medications without first speaking with your provider.
Frequently Asked Questions
There is no evidence of this.
PDE5 inhibitorsare a class of drugs used in the first-line treatment of erectile dysfunction.
National Institute of Diabetes and Digestive and Kidney Diseases.Symptoms & causes of erectile dysfunction.
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MedlinePlus.Drugs that may cause erection problems.
Med Clin (Barc).
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Kalejaiye O, Almekaty K, Blecher G, Minhas S.Premature ejaculation: challenging new and the old concepts.F1000Res.
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