FentanylandDilaudid (hydromorphone)are two potent opioid pain relievers.
There are some crucial nuances between fentanyl and Dilaudid.
This article delves into how they work, conditions they treat, safety considerations, and alternatives.
Richard Bailey / Getty Images
Richard Bailey / Getty Images
Which Is Better?
Your healthcare provider will help determine which is better for your situation.
It’s available 24/7.
What Is Fentanyl?
Fentanylis a powerful opioid pain medicine that is synthetic (made in a lab).
It’s 50 times more potent than heroin and 100 times more potent than morphine.
Activation of this receptor helps with pain relief and causes feelings ofeuphoria.
Symptoms of an overdose (taking too much fentanyl) include:
What Is Dilaudid?
If you suspect someone has overdosed, call 911 right away.
Naloxone products are available with a prescription or over-the-counter (OTC).
Contraindications
Some populations shouldnotuse fentanyl or Dilaudid due to safety risks.
For instance, fentanyl patches should not be used by people who haven’t taken opioid medications before.
People who use fentanyl patches should be “opioid-tolerant.”
This can cause breathing problems or death.
Some medications can interact with both fentanyl and Dilaudid.
Discuss any questions about how to take your medication with your healthcare provider or pharmacist to ensure safety.
Summary
Fentanyl and Dilaudid are two strong opioid medications used to treat some types of pain.
Illegally-manufactured fentanyl is currently the driver of the opioid epidemic.
When mixed with other recreational drugs, it’s hazardous.
Some populations shouldn’t take them due to safety concerns.
If you are prescribed fentanyl or Dilaudid, be sure to take it exactly as directed for optimal safety.
Never share it with others, and plan to keep Narcan on hand in case of an overdose.
Perez-Mana C, Papaseit E, Fonseca F, et al.Drug interactions with new synthetic opioids.Front Pharmacol.
2022;239(7):2063-2081. doi:10.1007/s00213-022-06125-5
Dydyk AM, Jain NK, Gupta M.Opioid use disorder.
Treasure Island (FL): StatPearls Publishing; January 17, 2024.
Department of Justice/Drug Enforcement Administration Drug Fact Sheet.Fentanyl.
U.S. Food and Drug Administration.DURAGESIC (fentanyl transdermal system), CII prescribing information.
U.S. Food and Drug Administration.ACTIQ (fentanyl citrate) oral transmucosal lozenge prescribing information.
2022;10:842454. doi:10.3389/fped.2022.842454
Department of Justice/Drug Enforcement Administration Drug Fact Sheet.Hydromorphone.
National Institute on Drug Abuse.Naloxone DrugFacts.
U.S. Food and Drug Administration.FDA approves first over-the-counter Naloxone nasal spray.
2022;79(1):13-23. doi:10.1001/jamapsychiatry.2021.2669
Kelly RB, Willis J.Acupuncture for pain.Am Fam Physician.
2019;100(2):89-96.
2024;165(1):144-152. doi:10.1097/j.pain.0000000000003006
Kim S.The unsuspected threat of three opioid-like substitutes.Arch Psychiatr Nurs.
2017;125(5):1682-1703. doi:10.1213/ANE.0000000000002426
Ruoff GM.OTC analgesics vs opioids for pain management.J Fam Pract.
2022;71(6 Suppl):S29-S33.
2021;7(1):e000935.
2022;187(9-10):244-247. doi:10.1093/milmed/usab485
Centers for Disease Control and Prevention.Fentanyl.
