Understanding Diabetes Blood Tests
The fructosamine and A1C tests for diabetes both measureblood sugar.
The A1C has raised concern over potential misdiagnosis, meaning that additional tests like the fructosamine may be helpful.
A 2016 review concluded that the fructosamine test doesnt have enough evidence to support its use.

Verywell / Hugo Lin
However, the glycated albumin tests also have limitations.
Some of these factors also affect fructosamine tests.
A 2015 article also noted that glycated albumin testing is considered more reliable than fructosamine testing.

Get our printable guide for your next healthcare provider’s appointment to help you ask the right questions.
It is usually covered by health insurance.
A home-based fructosamine test was discontinued in 2002 because it wasn’t accurate.
The A1C test also needs to be done using certified and standardized methods.
If the results remain high, it shows you have not had good blood glucose control.
Reference Ranges for A1C
Fructosamine results may be considered alongside the HbA1C and other tests.
Get our printable guide for your next healthcare provider’s appointment to help you ask the right questions.
Other Considerations
Sometimes, the reliability of the fructosamine test can be compromised.
Therefore, patients should abstain from ascorbic acid supplements for a minimum of 24 hours prior to sample collection.
The Chinese herb Polygalae Radix may also affect results.
Take your time to review your results, and be sure to ask questions about anything you dont understand.
Frequently Asked Questions
Anemia does not affect blood glucose levels (blood sugar).
In response, a mathematical formula has been created to avoid incorrectglucometerreadings.
It is primarily used in countries outside of the United States.
In the US, it is more common to record measurements using Mg/dL (milligrams per deciliter).
By multiplying the mmol/L measurement by 18, you’ve got the option to convert it to Mg/dL.
Glycemic targets: Standards of medical care in diabetes2022.Diabetes Care.
2022;45(Supplement 1):S83S96.
2015;5(5).
2019 Feb 11;9(1):18-21. doi:10.1080/20009666.2018.1559432.
Hribal ML, ed.PLoS ONE.
2014;9(10):e111463.
doi:10.1371/journal.pone.0111463
American Diabetes Association Professional Practice Committee.15.
Management of diabetes in pregnancy:Standards of medical care in diabetes2022.Diabetes Care.
2022;45(Supplement_1):S232-S243.
doi:10.2337/dc22-S015
Johns Hopkins Medicine.Alternative markers of glycemia: fructosamine, glycated albumin, 1,5-AG.
American Diabetes Association Professional Practice Committee.2.
Classification and diagnosis of diabetes:Standards of medical care in diabetes2022.Diabetes Care.
2022;45(Supplement_1):S17-S38.
2021 Feb 1;88(2):81-85. doi:10.3949/ccjm.88a.
American Diabetes Association.Common terms.