It may fight inflammation, improve skin conditions like eczema, and treat other health conditions.
GLA supplements are made from primrose, borage, and black currant oils.
That means some supplement products may not contain what the label says.
Verywell / Anastasia Tretiak
No supplement is intended to treat, cure, or prevent disease.
As with many natural products, more extensive research is necessary.
People use GLA for various reasons, including to improve skin conditions and to fight inflammation.
Skin Conditions
Several studies have supported GLA-enriched supplements for skin conditions such asatopic dermatitis (eczema).
GLA supplements may contain borage, primrose, or black currant seed oils.
However, one review questioned the actual effectiveness of GLA-enriched supplements.
While a 2014 clinical trial suggested GLA from primrose oil may benefit children and adults with atopic dermatitis.
Rheumatoid Arthritis
Several studies have supported GLA-enriched supplements for rheumatoid arthritis.
However, other studies suggest its unclear if GLA-enriched supplements are effective for RA.
Supplement Facts
What Are the Side Effects of Gamma-Linolenic Acid?
As with many medications and natural products, side effects are possible with GLA.
However, a severe allergic reaction is a serious side effect possible with any medication, including supplements.
This might result in heart-related effects.
Until more high-quality and long-term clinical trials are available, consider using GLA for only a short period.
And these chemicals may also be present in breast milk.
Contact a healthcare provider to discuss the benefits and risks before taking GLA.
For this reason, take GLA with caution.
Dosage: How Much Should I Take Gamma-Linolenic Acid?
While there are some studies on GLA in humans, additional high-quality clinical trials are still necessary.
For these reasons, there are no guidelines on the appropriate dosage to take GLA for any condition.
If you take GLA, follow the label instructions or get advice from a healthcare provider.
What Happens If I Take Too Much Gamma-Linolenic Acid?
If you suspect youre experiencing life-threatening side effects, call 911.
Interactions
There is limited information about possible medication interactions with omega-6 fatty acids.
However, omega-6 fatty acids found in GLA may affect inflammation pathways and substances in your body.
These are the likely causes of symptoms and problems in several autoimmune diseases.
For these reasons, GLA might interact with other medications that affect inflammation or the immune system.
How to Store Gamma-Linolenic Acid
Carefully read the directions and packaging label on the container.
Store in a cool and dry place.
Discard after one year or as indicated on the packaging.
Avoid putting unused and expired medicines down the drain or in the toilet.
Visit the FDA website to learn where and how to discard of all unused and expired medicines.
Sources of Gamma-Linolenic Acid & What to Look For
There are several different sources of GLA.
GLA-containing supplements might also be combined with other ingredients.
GLA-enriched supplements are generally available in several forms, including capsules and tablets.
These supplements might also be available in the following formats:
Vegetarian and vegan options might also be available.
What may work for you will depend on your preferences and what you hope to get regarding effects.
Each product will work a bit differently, depending on the form.
Summary
GLA is an omega-6 fatty acid in borage, primrose, and black currant seed oils.
But, similar to many medications and natural products, side effects and medication interactions are still possible.
Before taking GLA, involve a registered dietitian, pharmacist, or healthcare provider in your decision.
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