HemophiliaA is a disorder that leads to nosebleeds, gastrointestinal bleeding, bruising, and more.
Treatment for hemophilia A continues to evolve.
Symptoms
Bleeding is the primary effect of hemophilia A.
Illustration by Ellen Lindner for Verywell Health
The severity of an episode depends on factor VIII level and the symptoms that occur.
Causes
Hemophilia A takes place if there is a decreased amount of factor VIII in the body.
This protein is part of the bodys natural ability to form blood clots.
When blood does not clot properly, bleeding may occur.
Genetic
Hereditary hemophilia A is inherited with an X-linked pattern.
Most females have two X chromosomes, and most males have only one X chromosome.
Recurrent bleeding into the joints can cause pain and reduce mobility.
This can be treated with physical therapy and exercises.
Among the FDA-approved products for hemophilia A treatment is a syntheticvasopressinknown as DDAVP.
It can be used as a nasal spray or injection to control bleeding in mild cases.
One version, called STIMATE, was recalled in 2020 and has not returned to market.
A generic version has been manufactured since.
Talk with your healthcare provider about its availability.
Coping
Hemophilia A is a lifelong condition, and it is not curable.
Your prognosis depends on the severity of your condition and your response to treatment.
You also need to stay active to build muscle strength and balance, which can help prevent injuries.
Summary
Hemophilia A can cause major and minor bleeding episodes.
The condition takes place if someone has a lower-than-normal level of factor VIII.
The most common treatments are factor VIII replacements and Hemlibra (emicizumab), which mimics factor VIII.
Some people develop an immune reaction to factor VIII replacement, and this problem requires special treatment.
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