Two common formulations of Dramamine are regular Dramamine (dimenhydrinate) and Dramamine Less Drowsy (meclizine).
The effects of regular Dramamine can last around four to eight hours.
Both formulations are best taken at least 30 minutes to an hour before any activity that causes motion sickness.
Getty Images / LAW Ho Ming
Getty Images / LAW Ho Ming
How Does Dramamine Work?
Depending on the formulation, Dramamine may contain either dimenhydrinate or meclizine as the main ingredient.
The active ingredient in regular Dramamine is dimenhydrinate.
It blocks histamine receptors in the brain and gut, preventing nausea and vomiting.
The active ingredient in Dramamine Less Drowsy is meclizine.
Meclizine is also an antihistamine, but it is formulated to provide relief for 24 hours while minimizing drowsiness.
How Long Does Dramamine Take to Work and How Long Does It Last?
The duration can vary based on the specific product and dosage.
The effects of any form of Dramamine take about 30 minutes to an hour to work.
This means you must take Dramamine 30 minutes to an hour before any activity that can cause motion sickness.
The effects of regular Dramamine tablets containing dimenhydrinate usually last around four to eight hours.
However, Dramamine Less Drowsy provides relief for 24 hours.
Despite this difference, both forms of Dramamine are safe for children 2 and older.
Dramamine also comes in a less drowsy version called Dramamine Less Drowsy.
This form of Dramamine contains an active ingredient called meclizine.
Compared to dimenhydrinate, meclizines effects can last 24 hours.
The major disadvantage is that meclizine can only be used in children 12 or older.
If your child is under 12, it’s advisable to take Dramamine containing dimenhydrinate instead.
The main ingredient in Dramamine, dimenhydrinate, contains a common chemical called diphenhydramine (Benadryl).
Both of these medications are first-generation antihistamines that cause drowsiness.
As mentioned, Dramamine is an antihistamine.
This class of medication can block a chemical called acetylcholine, which causes salvation and bowel movement.
When antihistamines block acetylcholine, they can cause dry mouth and constipation.
Blurry vision is another common side effect when taking Dramamine.
Meclizine, the active ingredient in Less Drowsy Dramamine, is also available under the brandBonine.
Medications are not the only option to help prevent motion sickness.
Summary
Dramamine is an OTC medication used to prevent motion sickness symptoms.
Regular Dramamine lasts about four to eight hours, whereas Dramamine Less Drowsy lasts 24 hours.
Frequently Asked Questions
The length of how long the drowsiness can last varies from person to person.
Typically, drowsiness can last four to six hours.
With continual use, your body will get used to medication, and the side effects will slowly disappear.
Dramamine takes about 30 minutes to an hour for the medication to work.
Take the medication before any activity that triggers motion sickness for optimal benefits.
Avoid drinking alcohol with Dramamine, as alcohol can increase the effects of drowsiness.
If you plan on drinking alcohol with Dramamine, avoid any activity that requires full alertness.
The author would like to recognize and thank Alexya Rosas for contributing to this article.
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