Hypothyroidism
Hypothyroidismis estimated to occur in about 20 percent to 30 percent of all patients taking lithium.
As with goiter, hypothyroidism generally develops within the first two years of lithium treatment.
Treatment of subclinical or overt lithium-induced hypothyroidism entails taking thyroid hormone replacement medication.
Verywell / Brianna Gilmartin
It’s not completely clear how hyperthyroidism develops with lithium therapy.
It’s possible that transient hyperthyroidism may be from the direct toxic effect of lithium on the thyroid gland.
Lithium may also induce thyroid inflammation, as evidenced by the production of thyroid auto-antibodies in some people.
Treatment of lithium-induced hyperthyroidism involves taking an anti-thyroid drug.
Lithium-induced thyroid problems can be easily detected and effectively treated.
Lazarus JH.Lithium and thyroid.Best Pract Res Clin Endocrinol Metab.
2009;23(6):723-33. doi:10.1016/j.beem.2009.06.002
Cleveland Clinic.Goiter: Management and Treatment.
Gitlin M.Lithium side effects and toxicity: prevalence and management strategies.Int J Bipolar Disord.
2013;6(1):3.
Published 2013 Feb 7. doi:10.1186/1756-6614-6-3
University of Washington Department of Medicine.Techniques: Thyroid Exam.
National Institute of Diabetes and Digestive and Kidney Diseases.Thyroid Tests.
Radiological Society of North America.Thyroid Scan and Uptake.
Joffe RT.How should lithium-induced thyroid dysfunction be managed in patients with bipolar disorder?J Psychiatry Neurosci.
