PSC is not thought to be directly inherited, but it is thought tohave a genetic component.
Bile is necessary for the digestion of fat and to carry waste out of the liver.
This damage eventually leads to scar formation andcirrhosis, which prevents the liver from performing its important functions.
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PSC does progress slowly in most cases, but it can also be unpredictable and life-threatening.
People with PSC can receive treatment to relieve symptoms and help them lead an active life.
On the whole, PSC is an uncommon disease.
The symptoms worsen as the disorder progresses with the following signs becoming more common.
Dye is inserted into the ducts so that they will show up when X-rays are taken.
The x-rays are then analyzed to determine if there are any problems with the bile ducts.
Less intrusive, laboratory tests can also detect PSC by abnormal serum levels in the blood.
A liver biopsy can be useful when the imaging modalities are not diagnostic or when overlap syndrome is suspected.
This procedure is done in a hospital setting on an outpatient basis with alocal anesthetic.
Lastly, an MRCP, specialized magnetic resonance imaging, can be used to detect the rare condition.
Treatments
There is no definitive treatment for PSC.
Research to find an effective medical treatment is currently underway.
The Mayo Clinic reportstypes of treatment for the itching and infection due to PSC.
For recurrent infections that may occur with PSC, antibiotics could be necessary.
Liver transplants offer a good quality of life for recipients.
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