This article covers the anatomy of testicles and why they can be of different sizes.
Asymmetrical testicles are not uncommon and are usually not a problem.
However, if you also have these signs and symptoms, you should tell your provider.

Verywell / JR Bee
These conditions are usually not serious or life-threatening but they do need to be looked at by a provider.
A self-check is commonly used as a preventive tool for testicular cancer.
How Are Testicle Conditions Treated?
The different conditions that can affect the testicles have different treatmentsand some do not need much treatment at all.
For example, orchitis is usually just managed with rest and possibly antibiotics if bacteria is the cause.
Cancer of the testicles often involves a combination of treatments like chemotherapy, radiation, and surgery.
Summary
Having one testicle that is always slightly larger than the other is often normal.
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