There is no known cure forankylosing spondylitis, but research is constantly expanding and evolving.

This article with cover recent advancements in ankylosing spondylitis research and new medications.

It will also discuss other treatment options.

Back pain

Siriporn Kaenseeya / EyeEm / Getty Images

Rinvoq (upadacitinib) was approved in April 2022.

Other advancements in ankylosing spondylitis research are on how the condition develops inside the body.

Researchers are finding that the gut plays an essential part in the equation.

Future Breakthroughs

Ankylosing spondylitis is a condition of interest for many researchers.

A quick look at the U.S. clinical trials search engineClinicalTrials.govand you will find over 400 studies currently in progress.

No one can predict future breakthroughs for ankylosing spondylitis research, but the future is promising.

Researchers are looking into both symptom management and ways to reverse the condition.

Medications for AS Progression

There are several medications available for ankylosing spondylitis treatment.

The first line of treatment is anNSAID.

NSAIDs reduce inflammation and pain and can prevent disease progression by limiting the amount of bone formation.

It is the first choice of biologic medication for ankylosing spondylitis.

Other medication options include Interleukin-17 (IL-17) and Interleukin-23 (IL-23) inhibitors.

The newest group of medications to treat ankylosing spondylitis is JAK inhibitors.

There is no one right medication for every person with ankylosing spondylitis.

Many people find great relief in a combination of medication and exercise.

Add-On Treatment Measures

Medication is not the only treatment for ankylosing spondylitis.

A holistic approach is important to maintain mobility and find pain relief.

This includes:

Many complementary and alternative medicine (CAM) treatments are also used to treat ankylosing spondylitis.

CAM treatments have not been thoroughly studied for ankylosing spondylitis.

However, that does not mean they won’t provide any benefits.

Summary

Ankylosing spondylitis is a chronic condition that affects the spine and other large joints.

Numerous therapies are available to treat the condition, however, there is no known cure.

Researchers are finding new medications, with the most recently FDA-approved medication coming out in April 2022.

With research always expanding and evolving, the future is promising with newtherapies for ankylosing spondylitis.

A Word From Verywell

The future is bright if you or someone you know has ankylosing spondylitis.

Research has identified genetic and environmental causes and is working on therapies to bring this condition to an end.

Currently, many different medications minimize symptoms and can even slow the progress of ankylosing spondylitis.

Taking care of your mental health is also important, ask your healthcare provider about local support groups.

No, you cannot cure ankylosing spondylitis through diet changes or medication.

Garcia-Montoya L, Gul H, Emery P.Recent advances in ankylosing spondylitis: understanding the disease and management.F1000Res.

2018;7:F1000 Faculty Rev-1512.

doi:10.12688/f1000research.14956.1

Spondylitis Association of America.New treatment approved for ankylosing spondylitis: FDA OKs first JAK inhibitor, tofacitinib.

Abbvie.Rinvoq (upadacitinib) approved by U.S. FDA as an oral treatment for adults with active ankylosing spondylitis.

2019;14:8521-8542. doi:10.2147/IJN.S216199

Spondylitis Association of America.Treatment of spondyloarthritis.

Spondylitis Association of America.Complementary treatments.