This article reviews how Tylenol and Advil work to treat headache pain.
It also describes the possible risks and how to safely use these popular, over-the-counter (OTC) painkillers.
This doesn’t necessarily mean that Tylenol is the lesser option for treating headaches.

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Tylenol may also be better when fever is involved, lowering temperatures more and longer than Advil.
Advil vs. Aleve
Aleve (naproxen)is another NSAID that can be for headaches.
It is considered equally effective as Advil but works longer.

Risks of Tylenol for Headaches
If taken in high doses, Tylenol cancause liver injury and damage.
This is especially true if you drink heavily while taking the drug.
Adults should not take more than 3,000 milligrams (mg) of acetaminophen per day.
You should take even less if you are 65 years or older.
Check the label of any medications you take as products like cold & flu medicines contain acetaminophen.
Risks of NSAIDs for Headaches
NSAIDs are well known to affect blood clotting if overused.
This can lead to gastrointestinal symptoms as well as the formation of stomach ulcers.
This, in turn, can increase blood pressure and contribute to heart disease.
You should also avoid NSAIDs before and just after surgery to reduce the risk of postoperative bleeding.
(This is why Tylenol is typically given after surgery instead of an NSAID.)
During pregnancy, Advil is not recommended.
Can OTC Painkillers Cause Headaches?
Choosing the one that is right for you will depend on your needs, preferences, and risk factors.
This can help reduce your risk of side effects, complications, and drug interactions.
Can You Take Tylenol and Advil Together?
Because these pain relievers work differently, it’s usually safe to take Tylenol and Advil together.
That said, these side effects are usually not serious and do not last very long.
Also, remember that Excedrin contains both aspirin (an NSAID) and acetaminophen.
You should not take any OTC painkiller for an unlimited period of time.
To prevent side effects, take the lowest dosage needed for the shortest amount of time.
How to Treat Headache at Home
Tension headachesare the most common kind of headache.
Research supports the use of either for most tension-punch in headaches.
However, Tylenol can be hard on the liver if taken too long or in high doses.
If you have liver disease or drink heavily, you should avoid Tylenol.
NSAIDs like Advil carry a risk of peptic ulcers, kidney failure, and high blood pressure.
Its always important to use such medications safely and effectively.
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