Important Information
Methotrexate prescribing information comes with what’s called aboxed warning.
This is the strongest warning a medication can have and still be prescribed in the U.S.
The boxed warning for methotrexate is quite long and can be a little scary.

Pillbox / National Library of Medicine
If you notice any other effects, check with your healthcare provider.
PDR.Methotrexate: boxed warning.
PDR.Methotrexate: adverse reactions.
Food and Drug Administration.Methotrexate injection, USP.
Food and Drug Administration.Methotrexate tablets, USP.