It works by lowering the activity of the immune system.

No interaction has been found between the two medications so far.

However, you should always consult your healthcare provider before starting a new medication.

Young Asian woman sitting on bed and feeling sick, taking medicines in hand with a glass of water

AsiaVision / Getty Images

AsiaVision / Getty Images

What Is Prednisone?

Prednisone is a synthetic corticosteroid.

It is different from hydrocortisone or cortisone.

More serious side effects can occur with long-term use.

Your provider may recommend a separate treatment for your symptoms or adjust your prednisone dosage.

People withtuberculosiswho are taking corticosteroids require additional monitoring due to the drugs potential in reactivating the disease.

Therefore, if you are on this medication, you should have those levels monitored by your healthcare provider.

Your provider may recommend a supplement to keep these levels balanced.

Stopping corticosteroids abruptly can lead to withdrawal symptoms.

Tylenol is a brand of acetaminophen.

Do not exceed 3,000 mg of acetaminophen in a 24-hour period.

Do not mix this drug with other medications containing acetaminophen.

If you are pregnant or breastfeeding, ask a healthcare professional about the risks before use.

Is it Safe to Take Prednisone With Tylenol?

Prednisone must be taken exactly as prescribed by your healthcare provider.

Never stop or reduce your prednisone dosage unless your provider directs you to.

If you have questions about your dosage, give your provider a call.

Can I Take Any Pain Reliever With Prednisone?

The use of these drugs together is associated with a high risk of gastrointestinal complications, including peptic ulcer.

Do not use acetaminophen if you have taken amonoamine oxidase inhibitor (MAOI)within the past 14 days.

This includes drugs that contain isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Serious interactions between warfarin and acetaminophen are known to occur.

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