Pamprin and Midol are over-the-counter (OTC) medications that can be used to relieve symptoms associated withmenstrual periods.
Each one is available in various formulations to address different symptoms.
This article will review the different formulations of each drug.

Getty Images /Scott Olson/ Staff
Getty Images /Scott Olson/ Staff
What Is Pamprin?
Pamprin is a brand-name OTC medication that helps relieve symptoms associated with menstrual periods.
It comes in formulations of different ingredients, strengths, and dosing.
Pamprin Multi-Symptom Maximum Strength
Pamprin Multi-Symptom Maximum Strengthis an OTC caplet that is taken by mouth.
The dosage is two caplets by mouth with water every six hours as needed.
Do not take more than eight caplets in 24 hours.
Pamprin Multi-Symptom Maximum Strength is not used in individuals under 12 years old.
It comes as a tablet that is taken by mouth.
Do not take more than eight tablets in 24 hours.
It is not routinely recommended for use in children and adolescents.
Therefore, check with a healthcare provider before using this medicine in adolescents.
Precautions for Pamprin Max Pain + Energy include:
What Is Midol?
Like Pamprin, Midol is available in several formulations and is used to help relieve symptoms of menstrual periods.
It is available OTC in several brand-name product forms.
This product helps temporarily relieve the following symptoms associated with periods.
Unlike the regular Midol Complete formulation, it does not contain caffeine.
Midol Bloat Relief
Midol Bloat Relief is available OTC and is a tablet taken by mouth.
This diuretic medicine helps temporarily relieve bloating and water weight gain associated with menstrual periods.
Each tablet contains pamabrom 50 mg.
This medication contains one ingredient: acetaminophen 650 mg.
The caplets should be swallowed whole and not crushed, chewed, dissolved, or split.
This medicine should not be used for more than 10 days unless under a healthcare provider’s supervision.
Precautions include:
Midol Heat Vibes
Midol Heat Vibes are not pills but heat patches.
They are available OTC.
These air-activated patches are for a single use and last up to eight hours.
The heat helps with pain and cramps and helps relax muscles.
Each product has different ingredients to target different symptoms.
National Library of Medicine DailyMed.Pamprin Multi-Symptom Maximum Strength.
Pray WS, Pray GE.Alleviating menstrual discomfort: PMS and dysmenorrhea.US Pharm.
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National Library of Medicine DailyMed.Pamprin Max Menstrual Pain Relief.
Focus Consumer Healthcare.Pamprin Max Pain + Energy.
National Library of Medicine DailyMed.Midol Complete.
Bayer Health Care.Midol Complete Caffeine Free Caplets.
National Library of Medicine DailyMed.Midol Bloat Relief.
National Library of Medicine DailyMed.Midol Long Lasting Relief.