Hives may also beidiopathic(meaning of no known cause).

Hives can affect people of any age on any part of the body.

They can also be generalized (widespread) or localized (limited to a certain area).

woman scratching on her arm while sitting on sofa at home

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Specific symptoms can help a healthcare provider to rule out possible causes and diagnose the reason.

In most cases, an episode is not serious.

However, a sudden, acute episode may be part of a severe allergic reaction calledanaphylaxis.

Urticaria or Hives rash on thigh

Reproduced with permission from © DermNet and © Raimo Suhonendermnetnz.org2023.

This photo contains content that some people may find graphic or disturbing.

Reproduced with permission from DermNet and Raimo Suhonendermnetnz.org2023.

Reproduced with permission from DermNet and Te Whatu Oradermnetnz.org2023.

Urticaria or Hives on the skin

Reproduced with permission from © DermNet and © Te Whatu Oradermnetnz.org2023.

There are also immune reactions that don’t involve IgE that can cause acute urticaria.

These include certain infections and diseases.

The timing, location, and severity of symptoms are also factored in.

Hives

anand purohit / Getty Images

The hives commonly appear as splotchy welts with raised edges and well-defined borders.

They tend to be less spongy than acute hives.

Studies suggest that between 80% and 90% of cases are idiopathic.

Close-Up of Spongy Hives

Heather L. Brannon, MD

Even with extensive diagnostics, a cause may never be found.

The term “dermatographism” means the ability to write on the skin.

Instead, efforts may be focused on preventing scratching or abrasion.

A person with hives on their skin

SYMFONIA / Getty Images

Chronic urticaria is associated with theautoimmune response.

Treatment

Treatment for hiveswill depend on the diagnosis and pop in of urticaria.

Acute hives are commonly treated with second-generation H1antihistaminesthat help relieve swelling and itching.

Appearance of the word “Dermatographia” on a human arm 15 minutes after the letters have been traced with a blunt object on the skin. A type of urticaria or “hives”, also known as dermatographic urticaria, dermatographism, or “skin writing”.

R1carver/Wikimedia Commons/CC-BY-SA-3.0

This includesBenadryl(diphenhydramine).

Chronic hive treatment usually begins with OTC antihistamines like Benadryl and Pepcid (famotidine).

Severe cases may require oral corticosteroids like prednisone or an even stronger injectable prescription medication likeXolair(omalizumab).

Hives may be acute, appearing quickly and usually resolving quickly on their own.

Many cases clear on their own without treatment, but antihistamines and other medications can relieve symptoms.

Talk with your healthcare provider about any episodes of hives that may need diagnosis.

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American Academy of Dermatology Association.Hives: overview.

PMID: 38078471

Schaefer P.Acute and chronic urticaria: Evaluation and treatment.Am Fam Physician.

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