That means some OTC supplement products may not contain what the label says.

The Benefits of Fish Oil

Omega-3 fatty acids are a key in of goodpolyunsaturated fats.

Even so, the benefits of OTC fish oil supplements remain largely unproven.

Omega 3 softgels

Verywell / Anastasia Tretiak

Most studies have concluded that they offer no benefit.

Currently, prescription fish oil supplements are reserved solely for the treatment of severehypertriglyceridemia(high triglyceride levels).

And, until you reach a certain threshold, you may get no benefit at all.

Omega 3 softgels

Verywell / Anastasia Tretiak

Lesser doses do little to alter triglyceride levels.

Prescription fish oil supplements address these shortcomings by ensuring that DHA and EPA doses are at therapeutic levels.

While OTC supplements are generally regarded as safe, their benefits are often presumed rather than proven.

Each is taken by mouth as a capsule.

Generic forms are available.

As a general rule, never exceed the dose listed on the manufacturers label.

And youll likely lower your triglycerides in the same way.

Self-treating any medical condition may end up causing more harm than good.

OTC fish oil supplements, however, come with a few more.

OTC omega-3 supplements should also be avoided by people with fish allergies.

The most common side effects are burping, upset stomach, and changes in taste).

If you have a known fish or shellfish allergy, speak with your healthcare provider before using either supplement.

Safety and Purity

Supplements and prescription drugs containing omega-3 fatty acids are not created equally.

Each is subject to different rules and regulations by the FDA.

Supplement labels arenotallowed to state that they can treat or prevent any medical condition.

The certification confirms that the ingredients are pure and as described on the product label.

Prescription drugs are regulated more stringently.

Information about recommended dosage and storage will be included.

Prescription fish oil supplements should be stored at 77 F (25 C).

Short excursions in temperature between 59 F and 86 F (15 C and 30 C) are acceptable.

Discard any expired medications.

Keep out of the reach of children and pets.

Summary

Over-the-counter and prescription fish oil supplements contain more or less the same ingredients.

National Institutes of Health Office of Dietary Supplements.Omega-3 fatty acids.

2016:65(11):16361645. doi:10.1016/j.metabol.2016.07.010

National Library of Medicine: DailyMed.Lovazaomega-3-acid ethyl esters capsule[drug label].

National Library of Medicine: DailyMed.Vascepaicosapent ethyl capsule[drug label].

2019;140(12):e673-e691.

doi:10.1161/CIR.0000000000000709

National Library of Medicine: MedlinePlus.Omega-3 fatty acids.