Unfortunately, it’s not all that uncommon a mutation.

As such, the mutation is seen to be a contributing rather than the sole factor for the disorder.

Environmental toxins and other genetic issues may also play a part.

Senior African American couple, man in wheelchair

Susan Chiang / Getty Images

Men tend to be affected slightly more than women.

The condition is known as ophthalmoparesis.

Vertical movement of the eyes is commonly affected.

As the condition worsens, the upward gaze may also be impacted.

Poor eyelid control may also occur.

The diagnosis of PSP is based largely on symptoms.

It is a process by which all other possible causes need to be excluded.

Amagnetic resonance imaging (MRI)scan of the brain stem may be used to support the diagnosis.

In cases of severe dysphagia, a feeding tube may be needed.

The prognosis for PSP is generally poor.

The disease gets progressively worse, with most people becoming severely disabled within 3 to 5 years.

The most common cause of death is pneumonia.

Frequently Asked Questions

Dudley Moore was diagnosed with progressive supranuclear palsy (PSP) in 1998.

It is unknown if progressive supranuclear palsy (PSP) is hereditary.

In: StatPearls [Internet].

Ling H.Clinical approach to progressive supranuclear palsy.J Mov Disord.

Coughlin DG, Litvan I.Progressive supranuclear palsy: advances in diagnosis and management.Parkinsonism Relat Disord.