Having only one copy of the gene does not cause the disease.
There have been many research studies examining whether sickle cell trait can affect a persons health.
Genetics
Genes are located on structures called chromosomes.
Illustration by Theresa Chiechi for Verywell Health
A defect in the beta globin gene causes sickle cell disease.
Hemoglobin carries oxygen in red blood cells.
Sickle cell trait describes the condition of having one copy of the gene that causes sickle cell disease.
Diagnosis
Sickle cell trait is diagnosed with a genetic test.
This is a blood test that can detect abnormal genes.
It can identify whether a person has any copies of the mutation that causes sickle cell disease.
Complications
The effects of sickle cell trait have been examined.
Researchers have studied whether it has any effects on health.
However, sickle cell trait is associated with some complications.
It is described as a tumor in the medullary region of the kidney.
This tumor does require treatment, and it can be aggressive.
Postoperative Complications
Complications can occur after surgery if you have sickle cell trait.
Prevention of post operative complications involves close maintenance of oxygen, fluids, and acid-base balance.
However, sickle cell trait is not associated with heat injury or heatstroke.
Summary
Sickle cell trait is a condition of having one sickle cell gene mutation.
Having sickle cell trait doesnt cause sickle cell disease.
You may also consider whether to use genetic testing for family planning purposes.
Frequently Asked Questions
No, they are not exactly the same.
People who have the mutation on both copies of the gene have sickle cell disease.
Most people who have sickle cell trait do not develop any symptoms.
The biggest risk of having sickle cell trait is passing it on to a child.
A child will develop sickle cell disease if they inherit the gene mutation from both parents.
Yes, sickle cell trait is genetic.
It is an inherited defect in the gene that codes for part of the hemoglobin molecule.
Centers for Disease Control and Prevention.What is sickle cell trait?
