Bisphosphonate medications have become acommon treatmentfor patients withosteoporosis.

Upset Stomach/Esophageal Inflammation

One of the most common side effects of bisphosphonate medications is stomach upset.

The medication can cause inflammation of the esophagus and even lead to erosions of the surface of the esophagus.

Woman pouring pills into her hand from pill bottle

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Osteonecrosis of the Jaw

Osteonecrosis is a problem that causes bone cell death.

Data suggests a higher chance of jaw osteonecrosis in patients taking bisphosphonate medications.

This complication may arise within a day, or possibly weeks or even months after starting bisphosphonate therapy.

If severe muscle or bone pain is a problem, stopping bisphosphonate medication should be considered.

Speak to your healthcare provider about your symptoms.

Researchhas investigated this finding to determine if the medication could contribute to these unusual types of fractures.

Atrial Fibrillation

Atrial fibrillationis an abnormal heart rhythm that can cause a rapid heartbeat.

In reviews of other data, however, this association was not seen.

Some of these other complications are possible but unlikely.

Patients taking bisphosphonates should discuss with their healthcare provider how long to continue the medication.

Your healthcare provider should be able to help you determine the best option given your specific circumstances.

National Library of Medicine: DailyMed.FOSAMAX- alendronate sodium tablet[drug label].

2020;80(15):1537-1552. doi:10.1007/s40265-020-01364-2