Stage 4 liver cancer is the most advanced form of the disease.

Liver cancer is relatively rare, with under 42,000 cases being diagnosed each year.

Staging helps determine how far cancer has spread and what treatments might be useful.

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This number is applied to each designation (e.g., T1 means one tumor).

Also, there may be cancers that don’t fall neatly into one of the predefined stages.

Symptoms

In the first stages of liver cancer, there may not be any symptoms.

Further, liver cancer signs and symptoms aren’t always directly related to the stage of the cancer.

How the disease affects each person is highly individualized.

Those hormones may cause signs and symptoms that affect other organs and systems besides the liver.

These can include:

Causes

Several risk factors may contribute to the development of liver cancer.

Diagnosis

A diagnosis of liver cancer is made after performing a battery of tests.

For confirmation, other tests are needed.

Treatment

Stage 4 liver cancer is not curable.

However, treatment can help manage its symptoms and progression.

Can Surgery Cure Stage 4 Liver Cancer?

Likely not, since the cancer has already spread to other areas.

A liver transplant is generally not an option for stage 4.

Tecentriq is a drug that can increase the ability of the body’s immune system to target the cancer.

It might be used along with another drug, Avastin, which is a monoclonal antibody.

Radiation Therapy

The use of high-energy particles is another potential treatment for stage 4 liver cancer.

EBRT is similar to an X-ray.

SBRT is a treatment technique that has been developed more recently and may help preserve healthy liver tissue.

SearchingClinicalTrials.govorNIH Clinical Research Studiesmay also prove helpful.

CancerCareand theAmerican Liver Foundationare two organizations that provide helpful information and services.

Stage 4 Liver Cancer Life Expectancy

The benchmark ofcancer prognosisis usually the five-yearsurvival rate.

This is the number of patients that have survived five years after a diagnosis.

It differs based on the stage of the cancer.

Stage 4 liver cancer falls under the distant group.

How Long Can You Live With Stage 4 Liver Cancer?

The overall five-year survival rate is 3%.

The median life expectancy for stage 4 liver cancer that is left untreated is less than four months.

Statistics can be helpful, but they must also be put into perspective.

Also, scientists, researchers, and physicians are always learning new things about treating liver cancer.

It’s important to keep in mind that statistics are, by their nature, based on historical data.

The overall five-year survival rate is 3%.

American Cancer Society.Liver cancer stages.

National Cancer Institute.Cancer stat facts: liver and intrahepatic bile duct cancer.

American Cancer Society.Signs and symptoms of liver cancer.

National Institute of Diabetes and Digestive and Kidney Diseases.Symptoms & causes of cirrhosis.

2015;19:223-238. doi:10.1016/j.cld.2015.01.001.

2017;23(47):8263-8276. doi:10.3748/wjg.v23.i47.8263

National Cancer Institute.Liver Cancer Causes, Risk Factors, and Prevention.

2015;15:60. doi:10.1186/s12876-015-0288-0.

2017;4:58. doi:10.3390/children4070058.

Asrani SK, Devarbhavi H, Eaton J, Kamath PS.Burden of liver diseases in the world.J Hepatol.

2019;70:151-171. doi:10.1016/j.jhep.2018.09.014.

Abdel-Rahman O, Cheung WY.The expanding role of systemic therapy in the management of hepatocellular carcinoma.Can J Gastroenterol Hepatol.

2018;2018:4763832. doi:10.1155/2018/4763832.

Surveillance, Epidemiology, and End Results (SEER) Program.Liver and intrahepatic bile duct cancer.

SEER survival rates by time since diagnosis, 2000-2016.

2018;13(10): e0206374.