Grapefruit juice inhibits the breakdown of certain medications
Yes,grapefruitjuice chock-full of vitamins and nutrients.
For many, a glass of grapefruit juice is a healthy way to start the day.
This could result in adverse effects, such as a dangerous muscle disorder or liver damage.
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More specifically, grapefruit juice inhibits the hepatic (liver) enzyme system P450, which breaks down drugs.
By messing with this liver enzyme, more active ingredient affects your body.
In other words, the effects of statin drugs are increased in people who drink grapefruit juice.
These P450 enzymes break drugs down by oxidizing them.
Grapefruit should not be eaten while taking Lipitor because it can cause a dangerous interaction.
Grapefruit contains substances called furanocoumarins, which interfere with liver enzymes that break down the medication.
2016;129(1):26-9. doi:10.1016/j.amjmed.2015.07.036
Bushra R, Aslam N, Khan AY.Food-drug interactions.Oman Med J. Trevor AJ, Katzung BG, Kruidering-Hall M. Antifungal Agents.
