However, grapefruit can interact with thyroid replacement medication, making it hard to adjust the right dose.
This diet was usually promoted without attention to exercise or any other dietary intervention.
Some of the participants were reported to have lost as much as 10 kilograms (about 22 pounds).

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The problem is that diet plans are never as simple as proponents claim.
And if you take thyroid hormone replacement therapy, grapefruit may cause more harm than good.
Thyroid Drug Interactions
Grapefruit can be a delicious and nutritious addition to a diet or meal plan.
But grapefruit poses a potential risk for people who take thyroid hormone replacement therapy.
Repeated doses of grapefruit juice may also inhibit the activity of hepatic (liver) CYP3A4.
Many thyroid drugs, includinglevothyroxine, rely on CYP3A4 for metabolization and absorption.
Other Medications Affected By Grapefruit Juice
Thyroid drugs are not the only agents affected by grapefruit.
It is important to speak with your healthcare provider to discuss whether grapefruit is appropriate for you.
A Word From Verywell
Insofar as weight loss is concerned, there are many options to consider.
A healthy, balanced diet that meets your nutritional needs is the best option.