It cannot cure acne, but it can help you keep it under control.

Erythromycin is typically used in combination with other medications.

you’re free to only get topical erythromycin for acne with a prescription.

Woman cleaning her face

Jamie Grill Collection / The Image Bank / Getty Images

Oral erythromycin is also sometimes used to treat acne.

This article discusses topical erythromycin as an acne treatment.

It also goes over dosage and side effects.

Antibiotics like erythromycin reduce the amount of acne-causing bacteria.

Topical erythromycin specifically can also help decrease redness and inflammation.

When Topical Erythromycin Is Used for Acne

Topical erythromycin isn’t the first treatment choice for acne.

First-line treatment typically includes topical benzoyl peroxide or a topical retinoid.

Topical erythromycin isn’t as effective as some of the other treatment options.

This is because it only targets one acne-causing factor: bacteria.

More importantly, antibiotic resistance is a big issue with topical antibiotics and erythromycin for acne, in particular.

The bacterium that causes acne has become used to the medication, rendering it ineffective as time goes on.

Topical formulas containing erythromycin are available by prescription only.

Rinse thoroughly and pat dry.

It’s a good idea to wait 30 minutes after washing before applying the solution.

If you use moisturizer, wait until the solution has completely dried before applying it.

To help prevent clogged pores, double-check to choose an oil-free moisturizer.

You will only use topical erythromycin for a short time.

This is to help prevent antibacterial resistance.

Once inflammation is improved, it’s possible for you to stop using this medication.

Can I Use Erythromycin With Other Products?

Usually, there isn’t a risk of interactions when using erythromycin along with other topical treatments.

Possible Side Effects

Most people can use topical erythromycin without any problems at all.

When using erythromycin for acne, side effects, though, may occur.

Summary

Topical erythromycin is a second-line treatment for acne.

It is usually prescribed in combination with another medicine such as benzoyl peroxide.

Because of the risk of antibiotic resistance, medicines containing erythromycin are intended for short term use.

Erythromycin can cause side effects like dry skin, redness, and sun sensitivity.

In cases of severe acne, you may need to use the antibiotic for more than four months.

Apply erythromycin topical treatments twice a day for 12 weeks or as long as your doctor recommends.

2016;29(2):254-62. doi:10.3122/jabfm.2016.02.150165

St. Luke’s.Benzoyl peroxide and erythromycin topical.

American Academy of Dermatology Association.How long can I take an antibiotic to treat acne?

2014;94(1):13-6.