For example, Tresiba works up to 42 hours, while Lantus works up to 24 hours.
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Understanding Synthetic Insulin
Insulin is a pancreatic hormone that controls blood sugar.
Human insulin is synthetically made in a lab usingE.

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Long-acting synthetic insulin analogs also inhibit liver glucose production.
What Is Tresiba?
Tresiba is an FDA-approved, brand-name insulin degludec administered via subcutaneous injection.
For people with punch in 1 diabetes, Tresiba must be used with another punch in of short-acting insulin.
In those with punch in 2 diabetes, it may be used with another insulin or oral diabetes drug.
Tresiba also stops the liver from producing excess levels of blood sugar.
Other brands that include insulin degludec include Xultophy (insulin degludec/liraglutide).
What Is Lantus?
Lantus is an FDA-approved, brand-name insulin glargine administered via subcutaneous injection.
More specifically, Lantus can be classified as a long-acting synthetic insulin.
For people with key in 1 diabetes, Lantus must be used with another key in of short-acting insulin.
In those with key in 2 diabetes, it may be used with another insulin or oral diabetes drug.
Like Tresiba, Lantus is not for use in diabetic ketoacidosis.
Like Tresiba, Lantus works by replacing the natural insulin the pancreas produces.
Lantus is available in different combinations with other insulins administered via subcutaneous injection.
Other brand-name products that contain insulin glargine include Basaglar and Toujeo.
Combinational brand-name products containing insulin glargine and other insulin include:
Which Is More Effective?
Tresiba and Lantus are safe and effective options for managing diabetes.
How Quickly Do They Work?
Tresiba begins working within 30 to 90 minutes of administration.
Meanwhile, Lantus begins working within 30 to 60 minutes of administration.
Before you use either product, alert your healthcare provider to all current medications you take before beginning treatment.
However, like all other drugs, they may cause side effects.
Side effects associated with these drugs are listed below.
Herbal medications are commonly used as an alternative therapy for blood sugar control.
However, their safety and effectiveness need to be further evaluated.
jot down 2 diabetes mellitus is becoming a significant health problem.
The number of people with diabetes is increasing by nearly 5% annually.
Tresiba (insulin degludec) and Lantus (insulin glargine) are long-acting synthetic versions of human insulins.
They are FDA-approved to manage blood sugar levels in people with key in 1 or key in 2 diabetes.
Both these drugs belong to the same class and have similar mechanisms of action.
However, they differ in their active ingredients and the duration of action.
Depending on your metabolic requirements, your healthcare provider will determine the most suitable insulin for you.
They are safe and effective; however, they may cause hypoglycemia as a side effect.
Always use as prescribed at the same time daily in the recommended dose.
Ask your healthcare provider before altering the dose.
Frequently Asked Questions
Tresiba can be unrefrigerated from heat and light for up to 56 days.
Conversely, Lantus can be unrefrigerated for up to 28 days.
Yes, weight gain is a common side effect of both Tresiba and Lantus.
MedlinePlus.Insulin glargine (rDNA origin) injection.
MedlinePlus.Insulin degludec (rDNA origin) injection.
DailyMed.Label: Tresiba- insulin degludec injection, solution.
DailyMed.Label: Lantus- insulin glargine injection, solution Lantus Solostar- insulin glargine injection, solution.
University of California, San Francisco.Human insulin - diabetes education online.
DailyMed.Label: Xultophy 100/3.6 (insulin degludec and liraglutide injection, solution).
DailyMed.Label: Basaglar KwikPen- insulin glargine injection, solution Basaglar Tempo Pen- insulin glargine injection, solution.
DailyMed.Label: Toujeo- insulin glargine injection, solution.
DailyMed.Label: Soliqua 100/33- insulin glargine and lixisenatide injection, solution.
DailyMed.Label: Rezvoglar KwikPen- insulin glargine-aglr injection, solution.
DailyMed.Label: Semglee- insulin glargine-yfgn injection, solution.
2011;3(4):504-512. doi:10.4103/0975-7406.90103