Triple-negative breast cancer recurrence after a mastectomy is one of the most aggressive types of cancer.
Recurrence rates after standard conventional therapy (surgery, chemotherapy, and radiation therapy) are around 25%.
Mastectomy may or may not be followed by radiation therapy.
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Chemotherapy is also given for TNBC.
It may be given before surgery (neoadjuvant chemotherapy), after surgery, or both.
Research suggests that TNBC appears to have many root causes.
Radiation and systemic treatments like chemotherapy are also used.
This indicates that cancer has begun to spread outside of the breast cavity.
An analysis of 390 cases found that the risk of local TNBC recurrence was higher in people under 50.
In addition, the risk was highest in those with two or more of these factors.
The stage denotes how far cancer has spread at the time of diagnosis.
The numbers are better for cancer found in the early stages.
Unfortunately, reporting local or locoregional recurrence numbers does not reflect that the vast majority of recurrence isdistant metastasis.
By definition, five-year statistics cannot show the effects of treatments introduced in less than five years.
Symptoms of Recurrence
Symptoms associated with recurrence vary depending on their location in the body.
Local recurrence symptoms mimic the symptoms people living with TNBC originally experienced before treatment.
Regional recurrence symptoms include:
More distant recurrence symptoms usually manifest as a combination of generalized and organ-specific symptoms.
Lifestyle modifications also decrease your general risk.
Even after initial success with conventional treatment such as mastectomy, recurrence rates remain high.
Breast-conserving surgery (lumpectomy) may be an option as recurrence rates are similar to those of mastectomy.
The treatment chosen will depend on the size of the tumor, stage, and other factors.
Early-stage TNBC has a lower rate of recurrence than advanced stages.
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Vijay Trisal, MD.
City of Hope.What is cancer recurrence?
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