When the criteria for named autoimmune diseases are not met, the condition is defined as UCTD.
There are 5 named autoimmune connective tissue diseases.
They are classified based on a combination of symptoms, physical exam findings, and antibody testing.

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About 80% of people with this condition have antibody testing that’s positive for anti-Ro or anti-RNP autoantibodies.
The treatment is typically focused on managing the symptoms.
Sometimes Plaquenil (hydroxychloroquine) a disease-modifying anti-rheumatic drug (DMARD) is used.
If improvement is insufficient, low dose oral prednisone may be added for a short time frame.
The Bottom Line
The prognosis for UCTD is surprisingly good.
Most cases remain mild, and symptoms are usually treated without the need for heavy-duty immunosuppressants.
Palindromic rheumatism(PR) is a bang out of inflammatory arthritis that causes joint pain and inflammation.
Yes, you’re able to live a normal life with UCTD.
Many people with UCTD have mild symptoms and may not even need treatment.
Studies show a low likelihood of the disease spreading to other organs.
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