Decongestants narrow these blood vessels, which then lets mucus drain so it’s possible for you to breathe.

Most over-the-counter (OTC) decongestants contain either pseudoephedrine or phenylephrine.

When you feel stuffy, it’s natural to expect a decongestant to help.

Closeup woman pouring medication or antipyretic syrup from bottle to cup

spukkato / Getty Images

But it might not always be the right choice.

This article will walk you through the types of decongestants and how they work.

It will also help you understand the risks and side effects of using decongestants.

What Are Decongestants Used For?

What Are Common Decongestants?

Over-the-counter (OTC) decongestants come in nasal sprays and in oral forms.

Common decongestants include the following:

Nasal sprays work faster than oral decongestants.

Don’t use them for longer than recommended, though.

They can irritate your nasal passages and make congestion worse.

Combination products like Tylenol Sinus, Advil Cold & Sinus, andAleve Cold & Sinusalso contain pain relievers.

These medicines may help with sinus headaches from congestion.

Always follow the dosage instructions on the label or provided by your healthcare provider.

you’re able to use most decongestants three to four times a day.

Extended-release versions are used once or twice a day.

Buying Pseudoephedrine

Pseudoephedrine is technically available over the counter.

Other brand-name drugs that contain pseudoephedrine include:

This drug also prevents ear problems from pressure changes.

This can be helpful for those why fly or scuba dive.

These products are still considered safe to use and can still be found in stores.

Because it constricts blood vessels, it’s also used in some hemorrhoid treatments.

Afrin Nasal Spray (Oxymetazoline)

Afrin and many other nasal sprays contain oxymetazoline.

This drug is used for congestion and to relieve nasal discomfort from colds and seasonal allergies.

The dosing schedule is typically every 10 hours or every 12 hours.

Other sprays that contain oxymetazoline include:

It’s also used in many generic nasal sprays.

Decongestants are chemically related to adrenaline, your bodys natural decongestant and stimulant.

Caffeine may enhance the stimulant effect and worsen side effects of these drugs.

Watch for nervousness and trouble sleeping.

Warnings and Contraindications

Most people can safely use decongestants, but they arent for everyone.

Don’t take decongestants if you have:

Some products contain a decongestant and a painkiller.

Check the label before taking these with any other drugs.

This will help keep you from taking too much of any one medication.

Always tell your healthcare provider about all medications you take, including OTC drugs.

This can help you avoid possibly dangerous side effects and drug interactions.

Warning About Decongestant Use in Children

Don’t give decongestants to children under 6.

Before giving them to kids between 6 and 12, talk to their healthcare provider.

Summary

Decongestants narrow the swollen blood vessels that cause congestion.

They work best against stuffiness triggered by allergies or viruses.

Decongestants come in many forms, including tablets, liquids, and nasal sprays.

Always follow the dosage directions.

When using multi-drug products, verify you aren’t taking other drugs with the same ingredients.

Check with your healthcare provider about use in children, during pregnancy and breastfeeding, and with chronic conditions.

Contact your healthcare provider if you have any severe side effects.

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