However, there is little scientific evidence and more research is needed.
That means some supplement products may not contain what the label says.
No supplement is intended to treat, cure, or prevent disease.

Verywell / Anastasia Tretiak
It’s unknown whether berberine would have the same effect against RSV inside a human body.
Canker Sores
Some people use goldenseal forcanker sores(ulcers in the mouth).
Diabetes
Goldenseal is sometimes used fordiabetes.
The berberine in goldenseal may slightly lower blood glucose (sugar) in people with this condition.
Berberine may encourage your pancreas to secrete more of a naturally-occurring hormone calledinsulin.
And berberine may make your muscle and fat cells more sensitive to insulin’s effects, decreasing sugar levels.
When you take goldenseal by mouth, however, only a small amount is absorbed into the bloodstream.
Immune System Support
As a supplement, goldenseal is sometimes used to boost immunity.
It is commonly combined with echinacea for the prevention of the common cold and other viral illnesses.
However, there hasn’t been any good scientific evidence to support this use.
One study group took 5 mg of goldenseal powder per kg of body weight daily for eight weeks.
A second ground took 10 mg of goldenseal powder per kg of body weight daily for eight weeks.
A control group received no goldenseal powder.
The control group had slightly increased uric acid levels.
Supplement Facts
What Are the Side Effects of Goldenseal?
Like many medications and natural products, side effects are possible with goldenseal.
What Happens if I Take Too Much Goldenseal?
Instead, you should take it for short periods of time and only at the recommended dose.
If you suspect you’re experiencing life-threatening side effects, seek immediate medical attention.
They’ll monitor you for side effects and effectiveness issues and might adjust your medications.
Discard after one year or as indicated on the packaging.
Avoid putting unused and expired medicines down the drain or in the toilet.
Visit theFDA’s websiteto determine how to discard all unused and expired medicines.
They can help prevent possible interactions and side effects.
They can also ensure youre giving these supplements a fair trial at appropriate doses.
Sources of Goldenseal and What to Look For
There are several different sources of goldenseal.
Goldenseal Supplements
Goldenseal supplements are available in various forms, including capsules and tablets.
Each product may work a bit differently, depending on the form.
Thus, following your healthcare provider’s recommendations or label directions is essential.
Instead, these products contain other ingredients not listed on the label.
Look for products tested by a trusted independent party, such as USP, ConsumerLab, or NSF.
This information should appear on the label.
Independent testing will confirm whether or not a product contains the ingredients listed on the label.
Summary
Goldenseal is an herb native to the United States.
Similar to many natural products, people may use goldenseal for various reasons.
Goldenseal contains a complex mix of substances and chemicals, such as berberine.
And while there are more studies on berberine, they may not always apply to goldenseal.
Like many medications and natural products, it’s possible to have side effects and medication interactions with goldenseal.
Well-designed and long-term clinical trials are necessary to better assess goldenseal’s effectiveness and safety.
Before taking goldenseal, contact your pharmacist or healthcare provider to help you safely achieve your health goals.
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