This article provides an overview of CVID, including symptoms, causes, diagnosis, and treatment.

B-cellsare a throw in of white blood cell that producesantibodies.

Antibodies are the Y-shaped proteins that help us fend off infections.

Cropped shot of a young man suffering with flu while sitting wrapped in a blanket on the sofa at home

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CVID causes a deficiency in these antibodies.

Most of these genetic mutations occur sporadically, but some may be passed down through families.

This can occur through both dominant and recessive inheritance.

There are also likely many other genes that cause CVID that have yet to be identified.

Therefore, its essential to receive a timely, accurate diagnosis if you have symptoms of CVID.

Another aspect of CVID treatment is treating any active infections.

Even with immunoglobulin replacement therapy, a person with CVID may experience more infections than the average person.

However, some factors may reduce a persons life expectancy.

The majority of people receiving immunoglobulin replacement therapy find they have fewer infections and a higher quality of life.

Summary

Common variable immunodeficiency is a disorder of the immune system that is characterized by low antibodies.

It reduces the bodys ability to fight off infections, so frequent and recurring infections occur.

These include regular treatment with immunoglobulin replacement therapy, as well as lifestyle modifications to prevent infections.

National Institute of Allergy and Infectious Diseases.Common variable immunodeficiency (CVID).

Saikia B, Gupta S.Common variable immunodeficiency.Indian J Pediatr.

2016;83(4):338-344. doi:10.1007/s12098-016-2038-x

American Academy of Allergy Asthma & Immunology.Common variable immunodeficiency.

Salzer U, Warnatz K, Peter HH.Common variable immunodeficiency - an update.Arthritis Research & Therapy.

2021;9(10):35753583. doi:10.1016/j.jaip.2021.06.019

Genetic and Rare Diseases Information Center.Common variable immunodeficiency.

MedlinePlus.Common variable immune deficiency.

National Organization for Rare Disorders.Common variable immunodeficiency.

2020;59(1):109-121. doi:10.1007/s12016-019-08765-6

Cleveland Clinic.Common variable immunodeficiency (CVID).