They are needed to break down homocysteine.
Having too much of this amino acid is linked with a greater risk of many health problems.
These includestroke,blood clots, andheart attacks.

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The problem may also be linked with a higher risk of death from any key in of disease.
Symptoms occur due to low levels of the key B vitamins and/or folate.
A blood test can confirm the source of your symptoms.
Treatment involves changing your diet to restore low levels of B vitamins and folate.
This article describes hyperhomocysteinemia, its symptoms, linked health problems, and risk factors.
It also details how your diet affects the condition.
As the plaque deposits build up, the artery walls can stiffen and thicken.
Hyperhomocysteinemia Symptoms
Hyperhomocysteinemia symptoms can vary by individual.
Symptoms cause effects that range from mild to severe.
Most ailments that occur are nonspecific to this condition.
you’ve got the option to also consume specific foods to increase levels of individual B vitamins.
If you are diagnosed with another condition, treatment for that problem may help reduce homocysteine levels.
People with a high homocysteine level typically have their levels checked about two to three times annually.
Summary
Hyperhomocysteinemia is an ailment in which blood levels of homocysteine are higher than the normal range.
Without these, the amino acid does not break down.
Low levels of these vitamins can cause symptoms like fatigue, headaches, and mouth sores.
High levels of homocysteine can increase your risk of certain health problems.
These conditions include heart disease, bone disease, and kidney disease.
Quitting smoking and cutting down on the amount of coffee you drink can also help.
Supplements may also be advised if low levels do not increase by eating the right foods.
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2015;14:6. doi:10.1186/1475-2891-14-6
MedlinePlus.Homocysteine test.
American Academy of Family Physicians.High homocysteine level: how it affects your blood vessels.
2019;20(1):231. doi:10.3390/ijms20010231
Harvard Health Publishing.Vitamin B12 deficiency can be sneaky and harmful.
National Institutes of Health.Vitamin B6.
National Institute of Health.Folate.
National Institutes of Health.Vitamin B12.
Chan School of Public Health.Folate (folic acid) - Vitamin B9.