Hypoalbuminemiais a bloodalbuminlevel of less than 3.5 grams per deciliter (g/dL).
Albumin is the most abundant protein in the bloodstream.
Low albumin levels cause swelling due to fluid buildup in the tissues.
JulieAlexK / Getty Images
Low levels are associated with generalized weakness, low muscle mass, and increased inflammation.
This article will discuss hypoalbuminemia, including its symptoms, causes, diagnosis, and management.
JulieAlexK / Getty Images
What Is Albumin and How Does It Relate to Hypoalbuminemia?
Albumin is a protein made exclusively bylivercells.
It comprises half of the protein content in a healthy individual’s bloodstream.
Albumin plays a diverse role in the body.
The following health conditions or scenarios may cause hypoalbuminemia:
What Are the Symptoms of Low Albumin?
It can also be generalizedwhat’s known asanasarca.
Other common symptoms of low albumin include unusual tiredness and generalized weakness.
Individuals with low blood albumin levels can also experience symptoms and signs related to the underlying cause.
Other notable symptoms include diarrhea in individuals withprotein-losing enteropathyand a remarkably distended belly inkwashiorkor.
What Does a CMP Measure?
During this procedure, large volumes of fluid are removed from the belly.
Are Albumin Infusions Helpful?
Albumin infusions for hypoalbuminemia in critical illness are controversial.
What Foods Are High in Albumin?
Possible Complications of Hypoalbuminemia
Hypoalbuminemia is associated with several poor medical outcomes.
Other possible complications of hypoalbuminemia include:
Whats the Outlook for Someone with Hypoalbuminemia?
Summary
Hypoalbuminemia refers to low blood albumin levels.
It has many potential causes, including kidney or liver disease.
201712(8):e0182997.
doi:10.1371/journal.pone.0182997
Trebicka J, Garcia-Tsao G.Controversies regarding albumin therapy in cirrhosis.Hepatology.
2021;14:11-21. doi:10.2147/IJNRD.S291348
Kodner C.Diagnosis and management of nephrotic syndrome in adults.Am Fam Physician.
2016;93(6):479-485.
2015;3:e1267.
2017;10:147-168. doi:10.2147/CEG.S136803
Smith A, Baumgartner K, Bositis C.Cirrhosis: diagnosis and management.Am Fam Physician.
2019;100(12):759-770.
2019 Jan 10;14:105-111. doi:10.2147/CIA.S189040
