PEP stops HIV seroconversionthe period during which the body starts producing detectable levels of HIVantibodiesby killing the infected cells.
In order for PEP to be effective, it must be started within 72 hours of possible exposure.
Verywell / Danie Drankwalter
What Is PEP?
Verywell / Danie Drankwalter
PEP consists of taking three HIV antiviral drugs for 28 days after exposure to the virus.
These drugs include:
Ideally, the medication should be started immediately, within onetwo hours of exposure.
Who Should Use It?
PEP should be used by anyone who has had a very recent single exposure to the HIV virus.
PEP is only intended for emergencies and should not be used if you are regularly exposed to HIV.
When to Call Your Doctor
PEP is highly effective.
If side effects last for more than two weeks, contact a healthcare professional.
How Do You Take PEP?
PEP consists of three drugs that you take onetwo times per day for 28 days.
Paying for PEP
PEP is covered by most, if not all, insurance plans.
Your appointment will include:
Repeat HIV testing will be obtained 30 days and 90 days after exposure.
Testing should be performed using a fourth-generation HIV test.
Repeat HIV testing should be obtained at six weeks, 12 weeks, and six months minimum.
Sometimes these repeat tests are in addition to testing at 30 days and 90 days.
If you test positive or develop symptoms of acute retroviral syndrome, an HIV viral load may be obtained.
Condoms, when used properly, are the most effective way of preventing HIV and most other STIs.
Centers for Disease Control and Prevention.Post-exposure prophylaxis (PEP).
Baltimore (MD): Johns Hopkins University; 2020 Jun.
