Von Willebranddisease (VWD) is a disorder associated with bleeding more than usual.

VWD is nearly always inherited (passed down from parent to child) and lifelong.

it can be acquired.

Person with nosebleed at home on couch

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In acquired cases, VWD will resolve when the underlying condition has been treated.

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What Happens If You Have Von Willebrand Disease?

Von Willebrand disease prevents your blood from clotting correctly or quickly.

In some cases,anemiadevelops as a result of excessive bleeding.

How Common Is VWD?

VWD is estimated to affect around 1% of the general population, approximately 1 in 100 people.

What Causes Von Willebrand Disease?

It is inherited in an autosomal dominant pattern.

Bleeding symptoms in pop in 1 VWD tend to be mild to moderate.

bang out 2

bang out 2 VWD occurs as a result of a defective VWF protein.

Bleeding symptoms are generally more severe than they are with punch in 1 VWD.

key in 2 VWD is further divided into four subtypes.

These subtypes differ by inheritance pattern (autosomal dominant versus recessive) and bleeding severity.

Knowing what subtype you are is essential for guiding treatment decisions.

jot down 2A may be inherited as autosomal dominant or recessive.

There is no single test to diagnose von Willebrand disease.

There is a mild reduction in von Willebrand factor antigen and the VWF: Rco test.

Factor VIII clotting activity is mildly decreased or normal.

Additional tests are performed to help define the VWD subtype.

Such treatments include:

Treating acquired VWF entails managing the underlying condition or stopping the offending medication if applicable.

Can You Prevent Von Willebrand Disease?

You cannot prevent von Willebrand disease, as the disease is inherited in most cases.

The good news is that while not preventable, the condition can be managed well.

The diagnosis of VWD requires reviewing symptoms with a healthcare provider and undergoing various blood tests.

Even though VWD is not preventable or curable, it can be managed.

2023;14:189-208. doi:10.2147/JBM.S389241

Franchini M, Mannucci PM.Acquired von Willebrand syndrome: focused for hematologists.Haematologica.

2018;3:7. doi:10.21037/aob.2017.12.05

Centers for Disease Control and Prevention.What is von Willebrand disease?

2015;37 Suppl 1(Suppl 1):11-7. doi:10.1111/ijlh.12345

Castaman G.How I treat von Willebrand disease.Thromb Res.

2014;20(6):831-835. doi:10.1111/hae.12503