While the effects of NAD+ supplementation look promising, more studies are needed to explore the benefits and risks.
Nicotinamide adenine dinucleotide, or NAD, can come in two forms:
NADH is different from NAD+.
you’re free to get these precursors through supplements or foods.
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NAD+ is not currently recommended for any of these conditions.
Large-scale studies are needed before these supplements can be recommended.
No supplement is intended to treat, cure, or prevent disease.
There aren’t many studies on the effects of NAD+ supplements in humans.
So, it is unknown how to dose these supplements.
Dosage will depend on your product and what you use it for.
Tryptophan, NMN, NR, and niacin or niacinamide food sources or supplements can increase NAD+.
Also, keep in mind that optimal dosing or duration of NAD+ supplements has not been established yet.
That means some supplement products may not contain what the label says.
However, consuming one of these supplements may have potential side effects that may be common or severe.
NMN and NR might be better tolerated than other NADs, although fewer studies about their effects exist.
Summary
NAD+ is essential for regulating metabolism and circadian rhythm.
As we age, levels of NAD+ decline.
Reduced levels of NAD+ are associated with conditions like mental decline, diabetes, and heart disease.
Niacin, niacinamide, NMN, and NR can all boost levels of NAD+ in the body.
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