About 10% of people assigned female at birth in the United States experience difficulty getting pregnant.

For pregnancy to occur, the ovaries must release a mature egg, and sperm must fertilize the egg.

The fertilized egg, known as an embryo, must then implant in the uterine lining.

A person injects a fertility drug in preparation for IVF or IUI

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Intrauterine Insemination

IUI is a simple procedure that usually takes place in a healthcare providers office.

The procedure may feel similar to aPap test.

People undergoing IVF may choose to use their own eggs or donor eggs.

The sperm used could be from a partner or donor.

Both IUI and IVF can be time-consuming and expensive.

It is important to understand your chances of success when determining which procedure is right for you.

The average success (pregnancy) rate worldwide is 9%.

Talk with your healthcare team about your individual case and your estimated success rate before beginning IUI.

You may be wondering if it is possible to choose the babys sex with IUI.

When using IVF, your healthcare team can conduct genetic screenings on the embryos to determine their sex.

In IUI, the provider can predict the sex when washing the sperm.

However, it is not possible to guarantee the desired sex with IUI.

In general, IVF is more expensive than IUI.

Call your insurance company to determine your coverage before seeking care.

IUI is less invasive and expensive than IVF.

They are both forms of assisted reproductive technology (ART) to achieve pregnancy.

IUI is less invasive and expensive than IVF but also less successful.

Talk with your healthcare provider about which procedure is right for you.

Talk with your insurance company before choosing a procedure and to understand your coverage.

National Institute of Child Health and Human Development.Assisted reproductive technology (ART).

Society for Assisted Reproductive Technology.The difference between IUI and IVF.

A literature review.BMC Womens Health.

2023;23(1):557. doi:10.1186/s12905-023-02717-1

Office on Womens Health.Infertility.

2024;30(2):174-185. doi:10.1093/humupd/dmad033

Planned Parenthood.What is IUI?.

2017;67(6): 385-392. doi:10.1007/s13224-017-1060-x

MedlinePlus.In vitro fertilization (IVF).

2021;11(11):CD005356.

doi:10.1002/14651858.CD005356.pub3

American College of Obstetricians and Gynecologists.Treating infertility.

2023;13(3):395. doi:10.3390/jpm13030395

Walls ML, Hart RJ.In vitromaturation.Best Pract Res Clin Obstet Gynaecol.

Society for Assisted Reproductive Technology.Frequently asked questions.

New York Presbyterian.Intrauterine insemination.