In most cases, sinus infections will go away within a few weeks, andantibiotics may not be necessary.
A Z-Pak is a five-day course ofazithromycinthat has been a common antibiotic for sinus infections.
Azithromycin is in the class of antibiotics known as macrolides.

Getty Images / digicomphoto
Getty Images / digicomphoto
What Is a Z-Pak?
Can a Z-Pak Treat a Sinus Infection?
Yes, a Z-Pak can be an effective treatment for bacterial sinus infections.
However, it is ineffective against viral sinus infections, which account for most sinus infections.
Moreover, a Z-Pak is no longer the recommended go-to antibiotic due to the risk of resistance.
It is crucial to see a healthcare provider to get a diagnosis.
Your healthcare provider will be able to determine whether a bacterium or virus is causing your infection.
Side Effects of a Z-Pak
Azithromycin is generally well-tolerated, but it can cause some side effects.
This is known as QT prolongation.
You may be at increased risk if you:
What Other Antibiotics Can Treat a Sinus Infection?
However, you should seek care if your symptoms are severe or last longer than 10 days.
If you have sinus infection symptoms, seeing a healthcare provider for a diagnosis is vital.
Frequently Asked Questions
Sinus infections can be effectively treated with a Z-Pak or the amoxicillin antibiotic.
What’s the most suitable depends on your circumstances.
However, some people may need antibiotics to treat a bacterial infection.
If you have a sinus infection, seeing a healthcare provider to get a diagnosis is essential.
The author would like to recognize and thank Leen Alyaseen for contributing to this article.
Centers for Disease Control and Prevention.Chronic sinusitis.
2015;152(2 Suppl):S1-S39.